JCOGP
Journal of Controversies in Obstetrics & Gynecology and Pediatrics

As of January 2023, our "Journal of Controversies Obstetrics & Gynecology and Pediatrics" has been published under the Medihealth Academy to publish all articles, reviews and case reports on Pediatrics, especially in the field of Obstetrics and Gynecology. In order to facilitate the citation of the articles, to take our place in internationally respected indexes and to reach a wider readership, we will pay attention to the fact that our article language is only English in terms of acceptance. This journal is indexed by indices that are considered international scientific journal indices (DRJI, ESJI, OAJI, etc.). According to the current Associate Professorship criteria, it is within the scope of International Article 1-d. Each article published in this journal corresponds to 5 points.

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Original Article
Does autoimmune disease affect in vitro fertilization results in normo-responder cases?
Abstract
Aims: This study aimed to assess the effects of autoimmune disorders on pregnancy outcomes in infertile women undergoing in vitro fertilization (IVF) treatment.
Methods: This retrospective cohort study was conducted between March 2022 and September 2023, involving 90 infertile women without autoimmune diseases as a control group and 96 infertile women with autoimmune diseases as a case group. The study investigated the impact of autoimmune diseases on IVF treatment outcomes. Single embryo transfer (ET) was performed on the fifth day in all patients. Autoimmune diseases included in this study as Hashimoto's disease, Rheumatoid Arthritis, Sjogren's syndrome, Systemic lupus erythematosus (SLE), Ulcerative Colitis, and Behcet's disease.
Results: There was no statistically significant association between the case and control groups regarding live birth rate (p>0.05). Similarly, no statistically significant association was found between the case and control groups concerning the clinical pregnancy rate (p>0.05). Our results revealed that total oocyte, pronuclear (PN), and metaphase II (MII) oocyte rates were statistically significantly higher in healthy infertile women (p<0.05). The number of attempts, anti mullerian (AMH) levels, total gonadotropin dose, and total days were similar between the groups (p>0.05).
Conclusion: Autoimmune diseases do not significantly affect pregnancy outcomes in women undergoing IVF. However, several factors, such as total oocyte, PN, and MII oocytes, clinical pregnancy rate (CPR), and live birth rate (LBR) levels, support the association between autoimmune diseases and IVF outcomes.

Keywords : Autoimmune disease, clinical pregnancy rate, in vitro fertilization, pregnancy outcomes, infertility

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Article available in :
Volume 2, Issue 1, 2024
Page : 19-23
https://doi.org/10.51271/JCOGP-0028
Article Information
Received : 27 Ara 2023
Accepted : 16 Oca 2024
Published : 29 Oca 2024
Corresponding Author :

Halime Çalı Öztürk: Bezmialem University, Department of Obstetrics and Gynecology, Istanbul, Turkey

[email protected]
Citation : Ağar M, Devranoğlu B, Çalı Öztürk H. Does autoimmune disease affect in vitro fertilization results in normo-responder cases?. J Controv Obstetr Gynecol Ped. 2024;2(1):19-23.

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