JCOGP
Journal of Controversies in Obstetrics & Gynecology and Pediatrics

As of January 2023, our "Journal of Controversies Obstetrics & Gynecology and Pediatrics" has been published under the Medihealth Academy to publish all articles, reviews and case reports on Pediatrics, especially in the field of Obstetrics and Gynecology. In order to facilitate the citation of the articles, to take our place in internationally respected indexes and to reach a wider readership, we will pay attention to the fact that our article language is only English in terms of acceptance.

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Original Article
Investigating the association between hyperprolactinemia and thyroid autoimmunity in women
Abstract
Aims: Hyperprolactinemia (HPRL), a condition characterized by elevated levels of prolactin (PRL) hormone, is considered to be related to various autoimmune diseases, such as thyroid autoimmunity (TAI). The association between HPRL and TAI still evokes controversy. Our study intends to examine the possible relationship between HPL and TAI in young women.
Methods: This retrospective study was done between January 2018 and December 2022, including 90 women with HPRL and 90 control subjects of similar age and gender. A retrospective examination was conducted on the medical records of 90 patients with HPRL to gather relevant data. Information regarding related parameters was analyzed and compared to the control group data.
Results: Our results found that thyroid stimulating hormone (TSH) levels were notably elevated in patients with HPRL compared to healthy women (2.24 vs. 1.86). Also, a statistically significant association between the case and control regarding serum free triiodothyronine (fT3) (p<0.05). No statistically significant difference was found between the case and control regarding serum free thyroxin (fT4) (p>0.05). Patients with HPRL demonstrated considerably higher anti thyroperoxidase antibody (anti-TPO) levels (46.08 vs. 43.95). Significantly elevated antithyroglobulin antibody (anti-Tg) levels were observed in patients with HPRL (1.07 vs. 0.84).
Conclusion: The study suggests a potential link between HPRL and TAI. Further research is needed to explore this relationship and its implications for patient care.

Keywords : Hyperprolactinemia, HPRL, thyroid autoimmunity, autoimmune diseases

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Article available in :
Volume 1, Issue 4, 2023
Page : 99-103
https://doi.org/10.51271/JCOGP-0022
Article Information
Received : 02 Eki 2023
Accepted : 19 Eki 2023
Published : 20 Eki 2023
Corresponding Author :

Murat Önal: Gynolife IVF Clinic, Lefkosa, Cyprus

[email protected]
Citation : Önal M, Çalı Öztürk H. Investigating the association between hyperprolactinemia and thyroid autoimmunity in women. J Controv Obstetr Gynecol Ped. 2023;1(4):99-103.

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