JCOGP
Journal of Controversies in Obstetrics & Gynecology and Pediatrics

As of January 2023, our "Journal of Controversies Obstetrics & Gynecology and Pediatrics" has been published under the Medihealth Academy to publish all articles, reviews and case reports on Pediatrics, especially in the field of Obstetrics and Gynecology. In order to facilitate the citation of the articles, to take our place in internationally respected indexes and to reach a wider readership, we will pay attention to the fact that our article language is only English in terms of acceptance.

eISSN: 2980-0579
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Online Manuscript System

Index
Review
Eating disorders associated with polycystic ovary syndrome, a literature review
Abstract
Polycystic Ovary Syndrome (PCOS) is a common enigmatic, heterogenous endocrine disorder with multisystem consequences affecting women at reproductive age. Most associated dysfunctions in PCOS patients include ovarian dysmorphology, hormonal imbalances, metabolic disturbances, and neuropsychological impairments. Emerging studies have shown a relationship between women with PCOS and eating disorders (ED). ED is described as a psychological disorder characterized by extreme and constant disruptions in eating behaviors that can negatively impact one’s mental health and status. Types of EDs include binge eating disorder (BED), bulimia nervosa (BN), anorexia nervosa (AN), other specified feeding or eating disorders (OSFED), and unspecified feeding and eating disorders (UFED). Understanding the clinical relevance of these associations and adding correct assessments of ED as a key determinant of eating behavior may contribute to the successful treatment of women with PCOS. Thus, this review aims to outline a more profound connection between the involvement of multiple eating disorders and related disordered eating in women with PCOS; it also establishes a wider overview regarding the prevalence of comorbidities in eating disorders. Furthermore, the majority of researchers advised that screening for eating disorders, PCOS phenotyping, and neuroimaging modalities can be utilized to provide a better health outcome in PCOS patients.

Keywords : Polycystic ovary syndrome, PCOS, eating disorders, bulimia nervosa, anorexia nervosa

Download Article


1. De Giuseppe R, Braschi V, Bosoni D, et al. Dietary underreporting inwomen affected by polycystic ovary syndrome: a pilot study. Nutr Diet.2019;76(5):560-566. doi:10.1111/1747-0080.12460
2. Dokras A, Stener-Victorin E, Yildiz BO, et al. Androgen excess-polycystic ovary syndrome society: position statement ondepression, anxiety, quality of life, and eating disorders in polycysticovary syndrome. Fertil Steril. 2018;109(5):888-899. doi:10.1016/j.fertnstert.2018.01.038
3. Suchta K, Smolarczyk R, Czajkowski K, Rudnicka E, Kokoszka A.Binge eating disorder-the point prevalence among polish womenwith polycystic ovary syndrome and validity of screening tool for thispopulation. Int J Environ Res Public Health. 2022;20(1):546. doi:10.3390/ijerph20010546
4. Pirotta S, Barillaro M, Brennan L, et al. Disordered eating behavioursand eating disorders in women in australia with and without polycysticovary syndrome: a cross-sectional study. J Clin Med. 2019;8(10):1682.doi:10.3390/jcm8101682
5. Tay CT, Teede HJ, Hill B, Loxton D, Joham AE. Increased prevalence ofeating disorders, low self-esteem, and psychological distress in womenwith polycystic ovary syndrome: a community-based cohort study.Fertil Steril. 2019;112(2):353-361. doi:10.1016/j.fertnstert.2019.03.027
6. Cetik S, Acikgoz A, Yildiz BO. Investigation of taste function andeating behavior in women with polycystic ovary syndrome. Appetite.2022;168:105776. doi:10.1016/j.appet.2021.105776
7. Paganini C, Peterson G, Stavropoulos V, Krug I. The overlap betweenbinge eating behaviors and polycystic ovarian syndrome: an etiologicalintegrative model. Curr Pharm Des. 2018;24(9):999-1006. doi:10.2174/1381612824666171204151209
8. Karacan E, Caglar GS, Gürsoy AY, Yilmaz MB. Body satisfactionand eating attitudes among girls and young women with and withoutpolycystic ovary syndrome. J Pediatr Adolesc Gynecol. 2014;27(2):72-77.doi:10.1016/j.jpag.2013.08.003.
9. Barrea L, Verde L, Vetrani C, Savastano S, Colao A, MuscogiuriG. Chronotype: a tool to screen eating habits in polycystic ovarysyndrome? Nutrients. 2022;14(5):955. doi:10.3390/nu14050955
10. Pitts S, Dahlberg SE, Gallagher JS, Gordon CM, DiVasta AD. Is ovarianreserve impacted in anorexia nervosa? J Pediatr Adolesc Gynecol.2021;34(2):196-202. doi:10.1016/j.jpag.2020.11.021
11. Greenwood EA, Pasch LA, Cedars MI, Huddleston HG. Obesity anddepression are risk factors for future eating disorder-related attitudesand behaviors in women with polycystic ovary syndrome. Fertil Steril.2020;113(5):1039-1049. doi:10.1016/j.fertnstert.2020.01.016
12. Söderqvist G, Naesse´n S. Androgens impact on psychopathologicalvariables according to CPRS, and EDI 2 scores: in women with bulimianervosa, and eating disorder not otherwise specified. J Steroid BiochemMol Biol. 2023;226:106217. doi:10.1016/j.jsbmb.2022.106217
13. Steegers-Theunissen RPM, Wiegel RE, Jansen PW, Laven JSE, SinclairKD. Polycystic ovary syndrome: a brain disorder characterized byeating problems originating during puberty and adolescence. Int J MolSci. 2020;21(21):8211. doi:10.3390/ijms21218211
14. Ilie IR. Neurotransmitter, neuropeptide, and gut peptide profile inPCOS pathways contributing to the pathophysiology, food intake andpsychiatric manifestations of PCOS. Adv Clin Chem. 2020;96:85-135.doi:10.1016/bs.acc.2019.11.004
15. Burnatowska E, Wikarek A, Oboza P, et al. Emotional eating andbinge eating disorders and night eating syndrome in polycystic ovarysyndrome-a vicious circle of disease: a systematic review. Nutrients.2023;15(2):295. doi:10.3390/nu15020295
16. Barberis N, Calaresi D, Cannavo` M, Verrastro V. Body mass indexand quality of life in individuals with polycystic ovary syndrome:dysmorphic concerns and eating disorders as mediators. Front PublicHealth. 2022;10:962083. doi:10.3389/fpubh.2022.962083
17. Rodino IS, Byrne S, Sanders KA. Disordered eating attitudes andexercise in women undergoing fertility treatment. Aust N Z J ObstetGynaecol. 2016;56(1):82-87. doi:10.1111/ajo.12407
18. Kolnikaj TS, Herman R, Janezˆ A, Jensterle M. Assessment of eatingdisorders and eating behavior to improve treatment outcomes inwomen with polycystic ovary syndrome. Life (Basel). 2022;12(11):1906.doi: 10.3390/life12111906
19. Stefanaki K, Karagiannakis DS, Raftopoulou M, Psaltopoulou T, PaschouSA, Ilias I. Obesity and hyperandrogenism are implicated with anxiety,depression, and food cravings in women with polycystic ovary syndrome.Endocrine. 2023;82(1):201-208. doi:10.1007/s12020-023-03436-1
20. Harada M. Pathophysiology of polycystic ovary syndrome revisited:current understanding and perspectives regarding future research.Reprod Med Biol. 2022;21(1):e12487. doi:10.1002/rmb2.12487
21. Risal S, Pei Y, Lu H, et al. Prenatal androgen exposure andtransgenerational susceptibility to polycystic ovary syndrome. NatMed. 2019;25(12):1894-1904. doi:10.1038/s41591-019-0666-1
22. Özgen Saydam B, Yıldız BO. Polycystic ovary syndrome and brain: anupdate on structural and functional studies. J Clin Endocrinol Metab.2021;106(2):e430-e441. doi:10.1210/clinem/dgaa843
23. Itriyeva K. The effects of obesity on the menstrual cycle. CurrProbl Pediatr Adolesc Health Care. 2022;52(8):101241. doi:10.1016/j.cppeds.2022.101241
24. Cesta CE, Ma§nsson M, Palm C, Lichtenstein P, Iliadou AN, Lande´n M.Polycystic ovary syndrome and psychiatric disorders: co-morbidity andheritability in a nationwide swedish cohort. Psychoneuroendocrinology.2016;73:196-203. doi:10.1016/ j.psyneuen.2016.08.005
25. Thannickal A, Brutocao C, Alsawas M, et al. Eating, sleeping andsexual function disorders in women with polycystic ovary syndrome(PCOS): a systematic review and meta-analysis. Clin Endocrinol (Oxf).2020;92(4):338-349. doi:10.1111/cen.14153
26. Ee C, Pirotta S, Mousa A, Moran L, Lim S. Providing lifestyle advice towomen with PCOS: an overview of practical issues affecting success.BMC Endocr Disord. 2021;21(1):234. doi:10.1186/s12902-021-00890-8
27. Yurci A, Dokuzeylül Güngör N, Güngör K, Hatırnaz Ş. Correlationof serum leptin and ghrelin levels with endocrine and reproductiveparameters in women with clomiphene citrate resistant polycystic ovarysyndrome. Turk J Obstet Gynecol. 2022:27;19(2):124-129. doi:10.4274/tjod.galenos.2022.84883
28. Annagür BB, Kerimoglu ÖS, Tazegül A, Gündüz Ş, Gençoglu BB.Psychiatric comorbidity in women with polycystic ovary syndrome. JObstet Gynaecol Res. 2015;41(8):1229-1233. doi:10.1111/jog.12696
29. Başar Gökcen B, Akdeveliogˆlu Y, Canan S, Bozkurt N. Increased riskof eating disorders in women with polycystic ovary syndrome: a case-control study. Gynecol Endocrinol. 2020;36(9):764-767. doi:10.1080/09513590.2020.1744554
30. Algars M, Huang L, Von Holle AF, et al. Binge eating and menstrualdysfunction. J Psychosom Res. 2014;76(1):19-22. doi:10.1016/j.jpsychores.2013.11.011
31. Krug I, Giles S, Paganini C. Binge eating in patients with polycysticovary syndrome: prevalence, causes, and management strategies.Neuropsychiatr Dis Treat. 2019;15:1273-1285. doi:10.2147/NDT.S168944
32. Garin MC, Butts SF, Sarwer DB, Allison KC, Senapati S, Dokras A.Ghrelin is independently associated with anti-mullerian hormone levelsin obese but not non-obese women with polycystic ovary syndrome.Endocrine. 2017;55(3):907-913. doi:10.1007/s12020-016-1210-4
33. Chen X, Kong L, Piltonen TT, Gissler M, Lavebratt C. Association ofpolycystic ovary syndrome or anovulatory infertility with offspringpsychiatric and mild neurodevelopmental disorders: a Finnishpopulation-based cohort study. Hum Reprod. 2020;35(10):2336-2347.doi: 10.1093/humrep/deaa192
34. Lee I, Cooney LG, Saini S, et al. Increased risk of disordered eatingin polycystic ovary syndrome. Fertil Steril. 2017;107(3):796-802.doi:10.1016/j.fertnstert.2016.12.014
35. Rodriguez-Paris D, Remlinger-Molenda A, Kurzawa R, et al. Psychiatricdisorders in women with polycystic ovary syndrome. Psychiatr Pol.2019;53(4):955-966. doi:10.12740/PP/OnlineFirst/93105
36. Lee I, Cooney LG, Saini S, Sammel MD, Allison KC, Dokras A.Increased odds of disordered eating in polycystic ovary syndrome: asystematic review and meta-analysis. Eat Weight Disord. 2019;24(5):787-797. doi:10.1007/ s40519-018-0533-y
37. Sirmans SM, Pate KA. Epidemiology, diagnosis, and management ofpolycystic ovary syndrome. Clin Epidemiol. 2013;6:1-13. doi:10.2147/CLEP.S37559
38. Siddiqui S, Mateen S, Ahmad R, Moin S. A brief insight into theetiology, genetics, and immunology of polycystic ovarian syndrome(PCOS). J Assist Reprod Genet. 2022;39(11):2439-2473. doi:10.1007/s10815-022-02625-7
39. Jeanes YM, Reeves S, Gibson EL, Piggott C, May VA, Hart KH. Bingeeating behaviours and food cravings in women with polycystic ovarysyndrome. Appetite. 2017;109:24-32. doi:10.1016/j.appet.2016.11.010
40. Chudzicka-Strugala I, Gole?biewska I, Banaszewska B, Brudecki G,Zwoz´dziak B. The role of individually selected diets in obese womenwith PCOS-A review. Nutrients. 2022;14(21):4555. doi:10.3390/nu14214555
Article available in :
Volume 1, Issue 4, 2023
Page : 104-110
https://doi.org/10.51271/JCOGP-0023
Article Information
Received : 04 Eki 2023
Accepted : 12 Eki 2023
Published : 20 Eki 2023
Corresponding Author :

Nur Dokuzeylül Güngör: Department of Obstetrics and Gynecology IVF Clinic, Bahçeşehir University Göztepe Medikal Park Hospital, İstanbul, Turkiye

[email protected]
Citation : Dokuzeylül Güngör N, Ghachem H, Ghachem T. Eating disorders associated with polycystic ovary syndrome (PCOS), a literature review. J Controv Obstetr Gynecol Ped. 2023;1(4):104-110

Read: 702
Cited: 0
Download : 879
_Footer