JCOGP
Journal of Controversies in Obstetrics & Gynecology and Pediatrics

As of January 2023, our "Journal of Controversies Obstetrics & Gynecology and Pediatrics" has been published under the Medihealth Academy to publish all articles, reviews and case reports on Pediatrics, especially in the field of Obstetrics and Gynecology. In order to facilitate the citation of the articles, to take our place in internationally respected indexes and to reach a wider readership, we will pay attention to the fact that our article language is only English in terms of acceptance.

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Original Article
The impact of vitamin D supplementation on reproductive outcomes in women with polycystic ovary syndrome: a randomized controlled trial
Abstract
Aims: This study aims to evaluate the effectiveness of vitamin D supplementation treatment on reproductive outcomes in women with polycystic ovary syndrome (PCOS).
Methods: The study involved 235 women aged 20-40 with PCOS who were seeking treatment at Private infertility Clinic in Turkiye. The participants were divided into two groups: 123 in the control group and 115 in the intervention group, chosen at random. Their age, body-mass index (BMI), education level, employment status, and PCOS symptoms were assessed. Statistical significance between the case and control groups was compared using the chi-squared and Fisher’s exact tests.
Results: There were no significant differences in age, BMI, education level, employment status, and PCOS symptoms such as menstrual irregularity, amenorrhea, hirsutism, hair loss and acne between the intervention and control groups (p-value>0.05). There were significant differences in clinical pregnancy rates (CPR) between the intervention and control groups (p-value<0.05). The two groups showed no significant differences in live birth rates and clinical miscarriage rates (p-value>0.05).
Conclusion: Based on the findings, it has been revealed that supplementing with vitamin D has a positive impact on CPR. Vitamin D supplementation may support the improvement of fertility in women with PCOS, although the exact mechanisms and effectiveness are still under study.

Keywords : PCOS, vitamin D supplementation, pregnancy rates, reproductive outcomes

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Article available in :
Volume 3, Issue 2, 2025
Page : 37-41
https://doi.org/10.51271/JCOGP-0046
Article Information
Received : 29 Oca 2025
Accepted : 15 Şub 2025
Published : 11 Nis 2025
Corresponding Author :

Nurgül Ulusoy: Private Gynecology and Obstetric Clinic, İstanbul, Turkiye

[email protected]
Citation : Ulusoy N, Ağar M, Çalı Öztürk H. The impact of vitamin D supplementation on reproductive outcomes in women with polycystic ovary syndrome: a randomized controlled study. J Controv Obstetr Gynecol Ped. 2025;3(2):37-41.

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